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Neuropathy

What Is Neuropathy?

Neuropathy, sometimes specified as peripheral neuropathy, involves damage to nerves outside the brain/spinal cord, causing numbness, tingling, burning pain, and weakness, usually in hands and feet. Common causes include diabetes, infections, and injuries, with treatment focusing on managing underlying conditions, medication, and lifestyle changes.

 

Symptoms Include

  • Sensory: Numbness, tingling ("pins and needles"), burning, stabbing pain, and extreme sensitivity to touch.

  • Motor: Muscle weakness, cramps, fasciculations (twitching), and loss of muscle mass.

  • Autonomic:Constipation, dizziness upon standing, excessive/lack of sweating, and sexual dysfunction.

  • Other: Lack of coordination, falling, and feeling as if wearing gloves/socks.

 

Types of Nerves Affected By Peripheral Neuropathy

  • Sensory Nerves: Responsible for touch, temperature, and vibration.

  • Motor Nerves: Control muscle movement.

  • Autonomic Nerves: Regulate involuntary functions like heart rate and digestion.

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What is neuropathy?

Neuropathy refers to damage or dysfunction of the peripheral nerves, which carry signals between the brain, spinal cord, and the rest of the body. This damage can affect sensation, movement, or organ function depending on which nerves are involved.

 

What are the most common symptoms of neuropathy?

Symptoms of neuropathy can vary but often include:

  • numbness or tingling in the hands or feet

  • burning or sharp pain

  • increased sensitivity to touch

  • muscle weakness

  • balance problems

Symptoms usually start in the feet or hands and may gradually spread.

 

What causes neuropathy?

Neuropathy can have many causes, including:

  • diabetes

  • vitamin deficiencies

  • nerve compression or injury

  • autoimmune conditions

  • infections

  • certain medications

In some cases, the exact cause may not be identified.

 

Is neuropathy the same as nerve damage?

Neuropathy is a general term that refers to damage or dysfunction of peripheral nerves. Nerve damage can occur for many reasons, and neuropathy describes the resulting symptoms and nerve changes.

 

Can neuropathy be reversed?

Whether neuropathy can be reversed depends on the underlying cause. In some cases, such as vitamin deficiencies or early nerve irritation, symptoms may improve significantly with treatment. In other cases, treatment focuses on managing symptoms and improving nerve health.

 

How can physical therapy help neuropathy?

Physical therapy can help improve strength, balance, circulation, and movement patterns. Therapy may include exercises to improve nerve mobility, stability training, and strategies to reduce fall risk and improve daily function.

 

Why does neuropathy often affect the feet first?

Peripheral nerves that travel to the feet are the longest nerves in the body, which makes them more vulnerable to damage. Because of this, symptoms such as numbness or tingling often begin in the feet before progressing upward.

 

Can exercise help neuropathy?

Yes. Regular, appropriate exercise can help improve circulation, maintain muscle strength, and support nerve health. Exercise programs should be tailored to the individual to avoid worsening symptoms.

 

What types of neuropathy exist?

There are several types of neuropathy depending on which nerves are affected:

  • Peripheral neuropathy – affects sensory or motor nerves in the limbs

  • Autonomic neuropathy – affects involuntary functions such as heart rate or digestion

  • Focal neuropathy – affects a single nerve

 

When should someone see a healthcare professional for neuropathy?

It is important to seek medical evaluation if symptoms such as numbness, burning pain, weakness, or loss of balance appear or worsen. Early evaluation can help identify the cause and guide appropriate treatment.

2026

National Institute of Neurological Disorders and Stroke

2024

Nicoletta Marchesi, Foroogh Fahmideh, Alessia Pascale, Massimo Allegri, Stefano Govoni

2019

Ivanizia S Silva, Rafaela Pedrosa, Ingrid G Azevedo, Anne-Marie Forbes, Guilherme Af Fregonezi, Mário Et Dourado Junior, Suzianne Rh Lima, Gardenia Mh Ferreira

2004

C M White, J Pritchard, L Turner-Stokes

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